Phosphatidylserine (PS) Fact Sheet

The decline of mental capacity with age is a rising concern. It is estimated two out of four Americans who live past age 85 will suffer from Alzheimers or other severe mental illness. Poor lifetime habits can promote these conditions, while healthy lifestyle habits can prevent, slow progression and in some cases reverse these conditions. Lack of exercise, a junk food diet, and diet sodas contribute to depriving the brain of oxygen and basic nutrients it must have to keep its circuits firing. This increases the risk for mental deterioration.

Phosphatidylserine (PS) belongs to a major nutrient class called phospholipids. Phospholipids are a major part of cell membranes and are essential to life. Highest amounts of PS are found in the brain, but is also present in every cell in the body. This nutrient revitalizes the brain, boosting energy and metabolic efficiency at the cellular level. PS facilitates the diverse activities that make the brain the intricate organ it is. This nutrient naturally supports the production, packaging, and release of the chemical transmitters that make the brain work.

Studies have shown that PS is the most consistently effective brain nutrient for different types of brain functions. PS is the single best nutrient for safely conserving and restoring crucial functions of the brain for people both young and old. This nutrient can be found in soy, but not in significant amounts unless concentrated. This nutrient must be supplemented.

Some Of Its Benefits Include
  • memory improvement
  • delay in memory loss
  • improved verbal articulation
  • reduction in anxiety
  • improved mood
  • improved ability to cope with stress
  • improved concentration

The key to PS being the number-one brain booster is the fundamental importance of cell membranes. By boosting membrane functions in cells throughout the brain, PS seems to boost many nerve transmitters while simultaneously boosting their coordinated effects within the entire brain. Studies have clearly shown that PS can turn back the clock on brain decline, particularly when combined with positive exercise and lifestyle habits.

It is recommended when you first start taking this nutrient it is important to saturated the cell membranes. Therefore, for the first month of taking PS, use 200 to 300 mg per day with meals. You should be able to identify changes within 3 weeks, such as remembering phones numbers, name recall, and attention. After the first month, taper down to 100 to 200 mg per day for maintenance.


[1]Kidd, Parris, PhD. Phosphatidyleserine. A Keats Good Health Guide, Keats Publishing. 1998
[2]Kirschmann, Gayla, & Kirschmann John, Nutrition Almanac 4th Ed. Nutrition Search Inc. 1996